Group Leader, Pharmacology and Screening Oncology

Group Leader, Pharmacology and Screening Oncology
Debiopharm Group, Switzerland

Experience
1 Year
Salary
0 - 0
Job Type
Job Shift
Job Category
Traveling
No
Career Level
Telecommute
No
Qualification
Doctorate
Total Vacancies
1 Job
Posted on
May 3, 2021
Last Date
Jun 3, 2021
Location(s)

Job Description

Debiopharm is an independent biopharmaceutical company based in Switzerland with an ongoing commitment to research in oncology and bacterial infections in order to improving patient outcomes and quality of life. Our main activities include drug development, drug manufacturing and digital health investment. Debiopharm International SA aims to develop innovative therapies that target high unmet medical needs. Bridging the gap between disruptive discovery products and real-world patient reach, we identify high-potential compounds for in-licensing, clinically demonstrate their safety and efficacy and then select large pharmaceutical commercialization partners to maximize patient access globally.
Here: https://apply.workable.com/debiopharm-group-sa/
Debiopharm International S.A. identifies high-potential compounds for in-licensing, conducts clinical development and then selects large pharmaceutical commercialization partners to maximize patient access across the globe.

For our Pharmacology and Screening group, sitting within the Translational Medicine organization based at our Headquarter in Lausanne, we are looking for a

Group Leader, Pharmacology and Screening Oncology

The Group Leader manages and develops a functional team of scientists within the Pharmacology and Screening Unit, specialized in the field of oncology. The Group Leader also takes an active role in delivering Pharmacology amp; Screening (Pamp;S) packages on assigned projects. The mission of the Unit is to understand how drugs work, to guide and accelerate drug development. At Debiopharm you will be at the forefront of the fight against cancer, and you will have the opportunity to work on a large range of new innovative medicines for patients. Efficacy is our mode of action, saving lives our collective target.

Your responsibilities will be but not limited to:

Management:

  • You establish well-defined and ambitious objectives, as well as clear responsibilities and processes for monitoring work, assessing results, and recognizing achievements
  • You drive engagement by empowering your team, creating a feeling of belonging, fostering open dialogue, and sharing ownership and visibility
  • You develop your team through individual development plans, ongoing feedbacks amp; coaching

Operations:

  • You develop, manage and report on the functional team activities defined in the Translational Medicine Development plan, and deliver Pamp;S data packages generated by external vendors:
  1. In vitro/in vivo pharmacology compounds selection and profiling, including off-target characterization
  2. Proof of concept in vivo studies PK/PD
  3. Mechanism of action studie
  • You represent the Pharmacology and Screening and Translational Medicine function in global core project teams and contribute to the elaboration of the drug development strategy
  • You determine, implement and manage the clinical pharmacodynamic biomarkers analyses, data analyses and reporting according to GCPs and GCLPs and you represent Pharmacology and Screening function in clinical study teams
  • You participate in the preparation of investigator drug brochure, informed consent forms, lab manual and clinical protocol, and report
  • You identify the intellectual property, inventions and innovation opportunities, and collaborate with legal department to feed DPI’s patent portfolio
  • You are responsible for the preparation of the pharmacology documentation (summaries for IND and IMPD, briefing documentation for health authorities)
  • You participate in external scientific communications (publications, poster and oral presentations, and press releases)
  • You participate in due diligences and contribute to in/out licensing activities as subject matter expert

Requirements

  • PhD in the field of biomedical research biomedical engineering or equivalentStrong experience in translational pharmacology (including expertise both in preclinical and clinical development) at least 10+ in pharma or biotech
  • First proven experience in working in drug development in oncology
  • Knowledge of GCP and ICH guidelines; animal welfare regulations, and relevant regulatory guidelines
  • First experience in leading and developing further your team and contributing to the department strategy
  • You are used in working in cross-functional team and fast-paced environment, and in leading your teams to achieve the milestones and objectives
  • Excellent communication skills (oral and written) in both English and French
  • You are solution-oriented, resilient to push forward the Ramp;D projects and look to work on complex and innovative compounds, willing to keep hands activities on assigned projects
  • You have excellent commend of data a

Job Specification

Job Rewards and Benefits

Debiopharm Group

Information Technology and Services - Bern, Switzerland
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